Margaret of the Blessed Sacrament was born in Beaune, France, on February 7, 1619.

Her parents, Pierre Parigot and Jeanne Battaille, were both middle-class influential and wealthy. They very quickly directed their child to an authentically Christian life. At the age of 12, Margaret lost both her parents and her uncle a priest, who had donated the ancient cloister to the Carmelites, could not do better than to deliver his niece to the custody of the nuns, entrusting them with the education of the pious girl.

Thus, on September 24, with special permission from the Superiors, she entered Carmel, receiving her First Communion on the same day from the hands of her uncle. According to the custom of the Order, a new name was given to her, which recalled the special grace that was granted that day to the fortunate child: "of the Blessed Sacrament".

From the time of her novitiate, she understood with surprising clarity that God had entrusted her with a particular mission. She was called to make known to the world the treasures of the Divine Childhood and the painful sufferings of the Saviour.

At the Beaune Carmel, Margaret found not only a deep understanding of her devotion and love for the Child Jesus, but also a very fertile soil in which the divine grain of wheat could take root and develop luxuriantly.

In the early years of her religious life, she had to suffer unspeakably under the often harsh and fierce assaults of the perverse enemy. Sometimes it seemed that the poor child had to struggle with "the principalities and the powers, against the rulers of this world of darkness, against the spirits of evil scattered in the air". But everything served only to purify her love, making sure that she took refuge only at the feet of the Little Jesus.

Every morning and every evening, Margaret spent a long time in prayer before the Little Jesus. When she fell seriously ill and felt her last hour was approaching, she insistently asked to be granted the joy of seeing her dear King of Grace carried close to the infirmary, to be able to look at him and make her ultimate sacrifice under his gaze.

She died in 1648, at the age of 20.

The decree on her heroic virtue was promulgated on December 10, 1905.